Margo Emont
Margo Emont

Margo Emont

I am an instructor in medicine at Harvard Medical School and in the lab of Evan Rosen at Beth Israel Deaconess Medical Center. I completed my PhD in the lab of Jun Wu at the University of Michigan where I studied the regulation of thermogenic adipocytes. My current work uses single nuclear RNA sequencing to study the heterogeneity of cell types in white adipose tissue and how cell type proportion and function are affected under different physiological conditions. In my free time, I enjoy knitting and crocheting, trying new resturants, and hanging out with my cat, Dr. Franklin.

Index

Grants and Fellowships
Presentations
Mentorship
Teaching Experience
Service

For a list of published works, see research.

Education:

Month/Year(s) Title Discipline (Mentor) Institution
06/2011 AB Biology University of Chicago
04/2018 PhD Molecular Physiology (PI: Wu) University of Michigan

Postdoctoral Training:

Month/Year(s) Title Discipline (Mentor) Institution
12/2017 -04/2022 Postdoctoral Fellow Endocrinology (PI: Rosen) Beth Israel Deaconess Medical Center

Faculty Academic Appointments:

Month/Year(s) Academic Title Department Institution
04/2022- present Instructor Medicine/Endocrinology BIDMC/Harvard Medical School

Grants and Fellowships

Past

Year(s) Grant title Funding Agency, Grant type and Grant number Official role on project Description of major goals
2016-2017 Regulation of Thermogenesis in Adipocytes Through TRPA1 NIH F31 DK112625 Role: PI This project sought to characterize the role that heat-sensing cation channel TRPA1 plays in the regulation of the thermogenic program in beige adipocytes.
2020-2022 Investigating the Regulation of IRF4 in Adipocytes NIH F32 DK124914 Role: PI This project sought to define the regulation of the transcription factor IRF4 in adipocytes under a variety of physiological stimulations, as well as to gain a more complete understanding of the transcriptional program controlled by IRF4 once activated.

Current

Year(s) Grant title Funding Agency, Grant type and Grant number Official role on project Description of major goals
2022- present Investigating the Regulation of Distinct Human Adipocyte Subpopulations NIH K01 DK134806 Role: PI This project seeks to further interrogate distinct subtypes of white adipocytes, first identified in our lab, by discovering the stimuli that predispose one subpopulation over another and ultimately create in vitro models of these subpopulations for further study.

Presentations

Local Presentations:

Year Title Meeting/Institution Location
2021 A single cell atlas of human and mouse adipose tissue Diabetes Research Group, Broad Institute of MIT and Harvard Boston, MA
2021 A single cell atlas of human and mouse white adipose tissue Metabolism Program, Cardiovascular Disease Initiative, and Kidney Disease Initiative, Broad Institute of MIT and Harvard Boston, MA

National Presentations

Year Title Meeting/Institution Location
2022 A single cell atlas of human and mouse white adipose tissue Keystone Symposium, Adipose Tissue and Metabolic Health Whistler, Canada
2023 A single cell atlas of human and mouse white adipose tissue Metabolism, Endocrinology, and Diabetes Conference, University of Michigan Ann Arbor, MI
2023 A single cell atlas of human and mouse white adipose tissue Metabolism Interest Group, National Institutes of Health Virtual

International Presentations

Year Title Meeting/Institution Location
2021 Adipose tissue sNuc-seq: challenges and opportunities Human Cell Atlas, Biological Network Seminar Virtual
2022 A single cell atlas of human adipose tissue Human Cell Atlas General Meeting Vienna, Austria

Mentorship

Year Name Current Position Mentoring career stage Mentoring Role Accomplishments
2011-2013 Mallory Morse, DDS, MD Resident in Oral and Maxillofacial Surgery, Jacobi Medical Center/Mt Sinai Beth Israel Undergraduate Direct supervisor contributed to project on the role of Laminin alpha 4 in adipocytes.
2014-2015 Nenita Maganti, MD Resident in Ophthalmology, University of Wisconsin School of Medicine Undergraduate Direct supervisor Co-author on publication “Using a 3D Culture System to Differentiate Visceral Adipocytes In Vitro”.
2018-2020 Gregory Westcott, MD Instructor, BIDMC/Harvard Medical School Research fellow Direct supervisor Published a co-first author paper, “Mesothelial cells are not a source of adipocytes in mice”.
2022 Johannes Weigel Medical student, Julius-Maximilians Universitat Wurzburg Medical student Direct supervisor Contributed to the development of an IRF4 cistrome in adipocytes and wrote a report on the subject.

Teaching Experience

Year(s) Role Class(es) Department/Institution Responsibilities
2010-2012 Laboratory Teaching Assistant Cell & Molecular Biology, Genetics, Developmental Biology, Biology for non-major premeds Biological Sciences Collegiate Division, University of Chicago Led weekly lab class, gave a short presentation on lab topics, assisted students in performing and interpreting experiments, graded lab reports, held office hours.
2015 Graduate Student Instructor Physiology 201 Department of Molecular & Integrative Physiology, University of Michigan Responsibilities: Led weekly discussion section in which weekly class topics were reviewed with students, prepared group exercises on those topics for discussion sections, graded coursework

Service